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NABP FPGEE - Foreign Pharmacy Graduate Equivalency Examination

Page: 12 / 13
Total 426 questions

Effect of cascara is:

A.

Decreases water absorption

B.

Stimulates segmentation

C.

Decreases meal-stimulated gastric acid secretion

D.

May increase triglycerides

E.

Afterload increase

Class of famciclovir is:

A.

NSAID

B.

Antidepressants

C.

Autonomic nervous system drugs

D.

Antivirals

E.

Oral hypoglycemics

Mechanism of action of ampicillin is:

A.

Inhibits cholesterol synthesis

B.

Inhibits transpeptidase

C.

Inhibits viral DNA polymerase

D.

Potentiates glucose-mediated insulin secretion

E.

Inhibits renal epithelial Na channels

For highly polar drugs (e.g. mannitol) what primarily determines elimination rate?

A.

Excretion rate

B.

Metabolism rate

C.

Absorption rate

D.

Distribution rate

E.

All of the above

Class of nitrogen mustard is:

A.

Aquaretics

B.

Alkylating agents

C.

Lipid lowering drugs

D.

Drugs affecting calcium homeostasis

E.

Antivirals

Mechanism of action of amyl nitrite is:

A.

dopamine antagonist

B.

Unknown

C.

Holds water in stool

D.

Potassium channel agonist

E.

Stimulates guanylate cyclase

A drug ending in the suffix (navir) is considered a ______.

A.

Antidepressant

B.

Protease inhibitor

C.

Beta antagonist

D.

H2 antagonist

Given F = .24, what is the overall hepatic clearance of morphine if the above patient has portal hypertension such that their hepatic blood flow is reduced by ½? Assume the clearance value given in the previous question is entirely hepatic clearance.

A.

30 L/hr/70 Kg

B.

60 L/hr/70 Kg

C.

120 L/hr/70 Kg

D.

250 L/hr/70 Kg

Mechanism of action of flunisolide is:

A.

Inhibits DNA gyrase

B.

Inhibits phosphodiesterase

C.

Inhibits phospholipase A2

D.

beta-2 agonist

E.

Competitively inhibits H2 receptors

Indication of clindamycin is:

A.

Benzodiazepine intoxication

B.

Hypercalcemia

C.

Kaposi's sarcoma

D.

Streptococcus pneumoniae

E.

Angina