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NABP NAPLEX - North American Pharmacist Licensure Examination

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Total 154 questions

A patient with acute pharyngitis caused by group A Streptococcus (strep throat) is allergic to penicillins (non- immediate type), which of the following is NOT recommended as treatment?

A.

Clindamycin

B.

Amoxicillin

C.

Cefalexin

D.

Clarithromycin

Which of the following medication may increase LDL?

A.

Amiodarone

B.

Lisinopril

C.

Hydrochlorothiazide

D.

Acetaminophen

E.

Cyclosporine

Which of the following is dichotomous variable?

A.

Sex

B.

Pain yes/ Pain no

C.

alive / dead

D.

Grade of Breast Cancer

E.

NYHA I-IV

Which of these cardiovascular drug classes is most associated with tachyphylaxis?

A.

ACE inhibitors

B.

Angiotensin-receptor blockers

C.

Direct renin inhibitors

D.

Calcium channel blockers

E.

Nitrates

Alteplase is ordered for a 72 YOM who weighs 68kg for Ischemic stroke. The ER physician would like you to dose. As an ER pharmacist you know the dose is 0.9 mg/kg IV (not to exceed 90 mg); give 10% of the total dose as an IV bolus over 1 minute, then give the remaining 90% as an IV infusion over 60 minutes. After reconstitution, the concentration of Altaplace is 1mg/ml. How many ml is needed for the bolus and how many ml is needed for the infusion? Round to the nearest ml.

A.

6ml IV bolus, followed by 55mL IV over 60 minutes

B.

4ml IV bolus, followed by 57mL IV over 60 minutes

C.

3ml IV bolus, followed by 58mL IV over 60 minutes

D.

8ml IV bolus, followed by 52mL IV over 60 minutes

E.

9ml IV bolus, followed by 82mL IV over 60 minutes

A 51-year-old patient, who takes a calcium channel blocker (CCB), reports that he is experiencing constipation. Which CCB is the patient most likely to be taking?

A.

Nifedipine

B.

Amlodipine

C.

Verapamil

D.

Diltiazem

A 23-year-old female presents to your clinic complaining of intermittent throbbing headaches that usually last for several hours and are made worse by the presence of light. She endorses occasional nausea without vomiting during the most severe episodes. Physical examination is unrevealing, and she has no significant past medical history.

Which of the following treatments is considered an abortive therapy for this patient’s underlying condition?

A.

Sumatriptan

B.

Gabapentin

C.

Amitriptyline

D.

Propranolol

E.

Diltiazam

A CD4 count of 180 cells per cubic meter may be evaluated as which of these?

A.

Very low

B.

Low

C.

High

D.

Severely high

How does pregabalin work in the treatment of seizures?

A.

Sodium channel blocker

B.

α2δ ligand

C.

AMPA receptor antagonist

D.

GABA agonist

E.

SV2A binder

You get an order for 5% amino acid 15% dextrose premixed parenteral nutrition solution, 2 L at 83mls/hr. Your pharmacy technician tells you there is manufacture’s backorder on those. How many ml of 20% dextrose would you need to provide the same amount of dextrose in 24 hrs?

A.

1000ml

B.

1400ml

C.

1500ml

D.

200ml

E.

2500ml